Reference of 19808-30-1, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 19808-30-1, name is 5-Bromopyrimidin-4(3H)-one. This compound has unique chemical properties. The synthetic route is as follows.
Step T1: 5-Bromo-4-methoxy-pyrimidine A mixture of 5-bromo-3H-pyrimidin-4-one (Step T2) (17.9 mmol) and POCI3 (179 mmol) was stirred at 80 C. for 1 h and concentrated. The residue was dissolved in CH2Cl2 (30 mL) and cooled to 5 C. MeOH (20 mL) was added and the mixture was stirred for at rt 1 h and concentrated. The residue was triturated in CH2Cl2 to afford the title compound as a white solid. ESI-MS: [M+H]+ 189/191 (MS 1).
According to the analysis of related databases, 19808-30-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; NOVARTIS AG; Cotesta, Simona; Furet, Pascal; Guagnano, Vito; Holzer, Philipp; Kallen, Joerg; Mah, Robert; Masuya, Keiichi; Schlapbach, Achim; Stutz, Stefan; Vaupel, Andrea; US2013/317024; (2013); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia