Application of 58536-46-2, Adding some certain compound to certain chemical reactions, such as: 58536-46-2, name is 4-(4-Bromophenyl)-2,6-diphenylpyrimidine,molecular formula is C22H15BrN2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 58536-46-2.
General procedure: After completely dissolving a compound represented by Chemical Formula E1-P2 (7.8 g, 13.9 mmol) and a compound represented by Chemical Formula E1-A (3.7 g, 13.9 mmol) in tetrahydrofuran (THF) (70 mL), potassium carbonate (5.8 g, 41.8 mmol) dissolved in water (40 mL) was added thereto. After introducing tetrakistriphenyl-phosphinopalladium (0.5 g, 0.418 mmol) thereto, the result was stirred for 8 hours with heating. After lowering the temperature to room temperature, the reaction was terminated, and then the potassium carbonate solution was removed to filter white solids. The filtered white solids were washed twice each with THF and ethyl acetate to prepare a compound represented by Chemical Formula E1 (6.5 g, yield 70%). MS[M+H]+=665
According to the analysis of related databases, 58536-46-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; LG CHEM, LTD.; HEO, Dong Uk; LEE, Dong Hoon; HUH, Jungoh; JANG, Boonjae; HAN, Miyeon; YANG, Junghoon; YUN, Heekyung; (301 pag.)US2020/48230; (2020); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia