703-95-7, Adding a certain compound to certain chemical reactions, such as: 703-95-7, 5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 703-95-7, blongs to pyrimidines compound.
DBU (2.58 mL, 17.2 mmol) was added to a solution of 5-fluoroorotic acid (3 g, 17.2 mmol) in DMF (10 mL) After stirring for 30 minutes, iodoethane (2.69 mg, 17.2 mmol) was added tothe solution and the mixture was heated to 6000 for 2 hours. Water (100 mL) was added to the mixture, and the resulting precipitate was collected by filtration, washed with water, and dried to give 48 ethyl 5-fluoroorotate. LC-MS ES m/z =200.9; Rt: 0.91 mm, method D.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,703-95-7, its application will become more common.
Reference:
Patent; JANSSEN SCIENCES IRELAND UC; JONCKERS, Tim Hugo Maria; MC GOWAN, David Craig; GUILLEMONT, Jerome Emile Georges; EMBRECHTS, Werner Constant J; MERCEY, Guillaume Jean Maurice; BUYCK, Christophe Francis Robert Nestor; BALEMANS, Wendy Mia Albert; RABOISSON, Pierre Jean-Marie Bernard; (50 pag.)WO2017/125506; (2017); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia