Extracurricular laboratory: Synthetic route of 90213-66-4

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 90213-66-4.

90213-66-4, Adding some certain compound to certain chemical reactions, such as: 90213-66-4, name is 2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine,molecular formula is C6H3Cl2N3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 90213-66-4.

Zinc powder (8700 ¡¤ 0g, 133piomicron1, 10 ¡¤ Oeq ?) was added portionwise to glacial acetic acid (3 ¡¤ 3L, 53 ¡¤ 2mo1.4 ¡¤ Oeq ¡¤) and acetonitrile (30 ¡¤ 0L) mixture was added to complete the reaction temperature was raised to 80 C for 14 hours, the reaction was complete by TLC.87] The reaction mixture was cooled to 25 C, suction filtration, the filtrate was concentrated under reduced pressure and added to 30L of ice water, precipitated a large number of pink solid, filtration, the filter cake washed with water (5L X 3), dried to give a white solid 1501.7g. Yield: 73.54%.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 90213-66-4.

Reference:
Patent; Nanjing Furunkaide Bio-pharmaceutical Co., Ltd.; Rong Liang; Li Jin; Li Hui; Jie Yuanping; Wu Xihan; Yang Minmin; (12 pag.)CN105949196; (2016); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia