Application of 7431-45-0, Adding some certain compound to certain chemical reactions, such as: 7431-45-0, name is 2-Phenylpyrimidine,molecular formula is C10H8N2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 7431-45-0.
General procedure: In a Schlenk tube, a solution of R3In (0.375 mmol, ~0.3M en THF) and the arylpyridine (0.25 mmol)were successively added to a solution of Rh(PPh3)3Cl (24 mg, 0.025 mmol) in chlorobenzene (20 mL).The mixture was stirred at 120 C during 48 h, and the reaction quenched by addition of dropsof MeOH. The solvent was evaporated and CHCl3 (25 mL) was added. The organic phase waswashed with aq. NH3 (5%, 15 mL), dried, filtered, and concentrated. The crude was purified by flash chromatography (Et2O/hexane) affording, after concentration and drying, the cross-coupling products.
According to the analysis of related databases, 7431-45-0, the application of this compound in the production field has become more and more popular.
Reference:
Article; Riveiros, Ricardo; Tato, Ruben; Sestelo, Jose Perez; Sarandeses, Luis A; Molecules; vol. 23; 7; (2018);,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia