Application of 34253-03-7, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 34253-03-7, name is Methyl pyrimidine-2-carboxylate. This compound has unique chemical properties. The synthetic route is as follows.
To a solution of methyl pyrimidine-2-carboxylate (25 g, 181 mmol, 1 equiv) in MeOH (500 mL) was added NaBHt (8.2 g, 217 mmol, 1.2 equiv) at 0C. The reaction mixture was stirred at room temperature for 4 hours. The reaction mixture was quenched with H2O (20 mL), concentrated in vacuo and the residue was purified by flash column chromatography (eluted with PE/EtOAc = 1/1) to afford the title compound pyrimidin-2- ylmethanol as a yellow oil (16 g, 80% yield). LC-MS : m/z 111.0 (M+H)+
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 34253-03-7, Methyl pyrimidine-2-carboxylate.
Reference:
Patent; ANNAPURNA BIO INC.; TANG, Haifeng; BOYCE, Sarah; HANSON, Michael; NIE, Zhe; (213 pag.)WO2019/169193; (2019); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia