Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. One of the three diazines (six-membered heterocyclics with two nitrogen atoms in the ring), it has the nitrogen atoms at positions 1 and 3 in the ring. 1722-12-9, formula is C4H3ClN2, Name is 2-Chloropyrimidine. The pyrimidine ring system has wide occurrence in nature as substituted and ring fused compounds and derivatives, including the nucleotides cytosine, thymine and uracil, thiamine (vitamin B1) and alloxan. Computed Properties of 1722-12-9.
Feckova, Michaela;Kahlal, Samia;Roisnel, Thierry;Saillard, Jean-Yves;Boixel, Julien;Hruzd, Mariia;le Poul, Pascal;Gauthier, Sebastien;Robin-le Guen, Francoise;Bures, Filip;Achelle, Sylvain research published 《 Cyclometallated 2-Phenylpyrimidine Derived Platinum Complexes: Synthesis and Photophysical Properties》, the research content is summarized as follows. A series of five platinum (II) complexes based on 2-phenylpyrimidine ligands have been designed. Pyridine and chloride were used as auxiliary ligands. These complexes exhibit a slightly distorted square-planar geometry. The nature and position of substituent on the Ph ring was thoroughly studied. The presence of an electron-donating substituent on the Ph ring in the para position of the platinum atom leads to a red shift of the lowest-energy absorption band, which corresponds to the HOMO→LUMO transition and permits to obtain phosphorescence in deoxygenated CH2Cl2 solution All compounds are emissive in the solid state with a significant red shift for complexes bearing electron-donating substituent on the Ph ring of phenylpyrimidine ligand.
1722-12-9, 2-Chloropyrimidine is a monochlorinated pyrimidine with plant growth regulating activity. Chloropyrimidine is a useful reagent in the preparation of antivirals and other biologically active compounds.
2-Chloropyrimidine undergoes cobalt-catalyzed cross-coupling reaction with aryl halides.
2-Chloropyrimidine is a molecule that can be synthesized by the oxidation of pyrimidine with hydrogen peroxide and hydrochloric acid. The reaction proceeds through an electrochemical process in which the oxidation catalyst is a platinum electrode. This reaction is catalyzed by the nucleophilic attack of malonic acid on the chloropyrimidine at the methylene group. This efficient method for making 2-chloropyrimidine has been applied to synthesize aryl halides, including phenyl chloropyrimidine and pyridyl chloropyrimidine, from their corresponding chloride and bromide precursors. The fluorescence properties of 2-chloropyrimidine have been studied in coordination chemistry, where it forms complexes with metal ions such as Mn2+. In this study, it was found that adsorption mechanisms are dependent on molecular size, charge density, kinetic energy, and adsorbent surface area., Computed Properties of 1722-12-9
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia