Ferris, J. P.; Joshi, P. C.; Lawless, J. G. published the artcile< Chemical evolution. XXIX. Pyrimidines from hydrogen cyanide>, Related Products of 15837-41-9, the main research area is pyrimidine formation prebiosis; hydrogen cyanide pyrimidine formation.
Dilute (0.1M) solutions of HCN condensed to oligomers at pH 8-9. Hydrolysis of these oligomers at pH 8.5 or with 6N HCl yielded 4,5-dihydroxypyrimidine as the most abundant pyrimidine product along with orotic acid and 5-hydroxyuracil. Thus, the 3 major N-containing classes of biomols. could have originated from HCN on the primitive earth. The observation of the formation of orotic acid and 4-aminoimidazole-5-carboxamide by the hydrolysis of the HCN oligomers suggested that once the initially formed pyrimidines and purines were consumed, those life forms persisted which evolved enzymes for the conversion of these intermediates to the pyrimidines and purines present in contemporary RNA.
BioSystems published new progress about Molecular evolution. 15837-41-9 belongs to class pyrimidines, and the molecular formula is C4H4N2O2, Related Products of 15837-41-9.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia