Ferris, J. P.; Joshi, P. C.; Edelson, E. H.; Lawless, J. G. published the artcile< Chemical evolution. XXX. Hydrogen cyanide: a plausible source of purines, pyrimidines and amino acids on the primitive earth>, Recommanded Product: 5-Hydroxypyrimidin-4(3H)-one, the main research area is hydrocyanate chem evolution; amino acid formation hydrocyanate prebiotic; pyrimidine formation hydrocyanate prebiotic; purine formation hydrocyanate prebiotic.
Dilute (0.1M) solutions of HCN condense to oligomers at pH 9.2. Hydrolysis of these oligomers yields 4,5-dihydroxypyrimidine, orotic acid, 5-hydroxyuracil, adenine, 4-aminoimidazole-5-carboxamide, and amino acids. These results, together with the earlier data, demonstrate that the 3 main classes of N-containing biomols., purines, pyrimidines, and amino acids may have originated from HCN on the primitive earth. The observation of orotic acid and 4-aminoimidazole-5-carboxamide suggests that the contemporary biosynthetic pathways for nucleotides may have evolved from the compounds released on hydrolysis of HCN oligomers.
Journal of Molecular Evolution published new progress about Amino acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 15837-41-9 belongs to class pyrimidines, and the molecular formula is C4H4N2O2, Recommanded Product: 5-Hydroxypyrimidin-4(3H)-one.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia