Antiviral activities of some newer 2′-fluoro-5-substituted arabinosylpyrimidine nucleosides was written by Fox, J. J.; Watanabe, K. A.; Schinazi, R. F.; Lopez, C.. And the article was included in International Congress Series in 1985.Application of 69256-17-3 The following contents are mentioned in the article:
The inhibitory activity of the title compounds I (R = Me, Et, CH:CHBr, CH:CHI, I; X = NH or O) against herpes simplex virus in in vitro assays in Vero cells was determined Cytotoxicity was also determined The uracil nucleosides showed better therapeutic indexes than the corresponding cytosine analogs. The 5-Me analogs were more effective but also more cytotoxic than the corresponding 5-Et analogs. In mice with herpes simplex virus infections, 2′-fluoro-5-ethylarabinosyluracil [83546-42-3] and 2′-fluoro-5-methylarabinosyluracil [69256-17-3] were effective in decreasing mortality without any toxic effects. This study involved multiple reactions and reactants, such as 1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione (cas: 69256-17-3Application of 69256-17-3).
1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione (cas: 69256-17-3) belongs to pyrimidine derivatives. Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. As nucleotides in DNA and RNA, pyrimidine nucleotide derivatives have a wide range of biological applications. For example, pyrimidine derivatives are useful in DNA repair studies involving cancer and epigenetics.Application of 69256-17-3
69256-17-3;1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione;The future of 69256-17-3;New trend of C10H13FN2O5;function of 69256-17-3