COA of Formula: C5H6N2O3On November 20, 1995 ,《Metabolism of ALS inhibitory herbicide Bispyribac-sodium [KIH-2023] in rats》 appeared in Nippon Noyaku Gakkaishi. The author of the article were Fukai, Yasushi; Unai, Tadaaki; Ishikawa, Kanji; Yusa, Yoshio; Wada, Nobuhide; Tezuka, Masakatsu; Okada, Shoji. The article conveys some information:
Absorption, distribution and metabolism of Bispyribac-sodium [sodium 2,6-bis(4,6-dimethoxypyrimidin-2-yloxy)benzoate] or [KIH-2023] in rats orally dosed with 14C-KIH-2023 were investigated. More than 90% of the dosed radioactivity was detected in the excreta within 96 h after dosing. Level of the radioactivity in the blood of male and female rats reached maximum at 2 and 1 h after dosing, resp., and then decreased rapidly to about a half level of maximum (C1/2). The radioactivity of tissues was lower at 96 h after dosing than that at C1/2-time. Most of the radioactivity in the urine, feces, liver, and plasma was detected as unchanged KIH-2023. The major radioactive compounds excreted into the bile were KIH-2023 and its glucuronide. Repeated oral administration of KIH-2023 for 15 days gave similar results from the single oral one in the excretion, tissue distribution and metabolism of 14C-KIH-2023. In the experiment, the researchers used many compounds, for example, 6-Methoxypyrimidine-2,4(1H,3H)-dione(cas: 29458-38-6COA of Formula: C5H6N2O3)
6-Methoxypyrimidine-2,4(1H,3H)-dione(cas: 29458-38-6) belongs to pyrimidine. Pyrimidine nucleotide derivatives have a wide range of biological applications. For example, pyrimidine derivatives are useful in DNA repair studies involving cancer and epigenetics.COA of Formula: C5H6N2O3
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia