Fun Route: New Discovery of 148-51-6

Here is a brief introduction to this compound(148-51-6)Electric Literature of C8H12ClNO2, if you want to know about other compounds related to this compound(148-51-6), you can read my other articles.

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Preparation of 5-hydroxy-4,6-dimethyl-3-pyridinemethanol (4-deoxypyridoxine) by the use of hydrazine, published in 1961, which mentions a compound: 148-51-6, mainly applied to , Electric Literature of C8H12ClNO2.

2-Methyl-3-hydroxy-4-methoxymethyl-5-hydroxymethylpyridine-HCl (10 g.) and 50 ml. 95% N2H4 refluxed 18 hrs., most of the N2H4 removed in vacuo, and the residue extracted with 60 ml. refluxing MeOH yielded N2H4.HCl, m. 91-2°. The volume of the filtrate reduced to 20 ml., 15 ml. 11.2% MeOH-HCl added, the precipitate isolated, and 50 ml. Et2O added gave a further precipitate The total yield was 8.1 g. 2-methyl-3-hydroxy-4-methyl-5-hydroxymethylpyridine-HCl (I), m. 273° (decomposition). All conditions and isolation procedures were as above except that instead of the 4-Me ether, 5 g. pyridoxine-HCl and 25 ml. 95% N2H4 were used to give 98% I.

Here is a brief introduction to this compound(148-51-6)Electric Literature of C8H12ClNO2, if you want to know about other compounds related to this compound(148-51-6), you can read my other articles.

Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia