Gacek, M. published the artcileMetahalones, a new class of metaphase inhibitors, Formula: C5H5ClN2S, the main research area is metahalone metaphase inhibitor; liver metaphase arrest metahalone; pyrimidine halogenated metaphase inhibition.
A total of 31 halogenated pyrimidine derivatives were tested for metaphase-arresting activity 6 h after addition to monolayer cultures of human liver cells (Chang strain). O-substituted derivatives were inactive, whereas N-substituted derivatives were active. The metaphase-inhibiting activity depended largely on the structure and substituent groups of the compounds tested. The name metahalones is suggested for this class of inhibitors: meta from metaphase, hal from halogen, and one because the activity was associated with the one-form of the 2-hydroxy group.
FEBS Letters published new progress about Liver. 38275-42-2 belongs to class pyrimidines, name is 5-Chloro-2-(methylthio)pyrimidine, and the molecular formula is C5H5ClN2S, Formula: C5H5ClN2S.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia