Recommanded Product: 18436-73-2. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 4-Chloro-8-methylquinoline, is researched, Molecular C10H8ClN, CAS is 18436-73-2, about Rapid Microwave-Assisted, Solvent-Free Approach to Functionalization of 8-Methylquinolines via Rh-Catalyzed C(sp3)-H Activation. Author is Zhu, You-Quan; He, Jing-Li; Niu, Yun-Xia; Han, Ting-Feng; Zhu, Kun.
A microwave-assisted synthesis of aryl (quinolinyl)acetamide derivatives I [R1 = H, 6-Cl, 4-Br, etc.; R2 = 3-Me, 4-F, 4-Cl, etc.] and quinolinyl (methyl)benzamide II via Rh-catalyzed C(sp3)-H activation of 8-methylquinoline under solvent-free condition was reported. In comparison with traditional method, this reaction proceeded more efficiently with excellent yield, a broad range substrate scope and good functional group tolerance.
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Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia