Clean synthesis and antibacterial activities of spiro[pyrimido[4,5-b]-quinoline-5,5′-pyrrolo[2,3-d]pyrimidine]-pentaones was written by Ghahremanzadeh, Ramin;Azimi, Seyyedeh Cobra;Gholami, Nader;Bazgir, Ayoob. And the article was included in Chemical & Pharmaceutical Bulletin in 2008.Name: 6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one This article mentions the following:
A simple, clean and efficient method for the synthesis of spiro[pyrimido[4,5-b]quinoline-5,5′-pyrrolo[2,3-d]pyrimidine]-pentaone derivatives by condensation reaction of 6-amino-uracils and isatins in aqueous media is reported. These products were evaluated in vitro for their antibacterial activities. In the experiment, the researchers used many compounds, for example, 6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one (cas: 54030-56-7Name: 6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one).
6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one (cas: 54030-56-7) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. Drugs having the pyrimidine motif have manifested to exhibit gratifying biological activity like anticancer, antiviral, anti-inflammatory, antibacterial, and antihypertensive activities.Name: 6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia