On March 31, 2022, Gimadieva, A. R.; Khazimullina, Yu. Z.; Abdrakhmanov, I. B.; Mustafin, A. G. published an article.Synthetic Route of 626-48-2 The title of the article was A Procedure for Preparing Effective Immunomodulators and Antioxidants: 5-Hydroxy-6-methyluracil and 5-Hydroxy-1,3,6-trimethyluracil. And the article contained the following:
5-Hydroxy-6-methyluracil is an acting agent of Oxymethyluracilum drug, an immunostimulator with a broad spectrum of pharmacol. activity. Its synthesis is based on the 6-methyluracil oxidation with (NH4)2S2O8 under the conditions of Elbs reaction. The Elbs oxidation of 6-methyluracil in the presence of metal phthalocyanine oxidation catalysts was studied. Conditions allowing the 5-hydroxy-6-methyluracil yield to be increased to 95% were found. The most active catalysts are Fe(II), Fe(III), and Co phthalocyanines. The experimental process involved the reaction of 6-Methylpyrimidine-2,4(1H,3H)-dione(cas: 626-48-2).Synthetic Route of 626-48-2
The Article related to hydroxymethyluracil hydroxytrimethyluracil preparation immunomodulator antioxidant, Biomolecules and Their Synthetic Analogs: Others, Including Purines, Pyrimidine Nucleic Acid Bases, Flavins, Lignans and other aspects.Synthetic Route of 626-48-2
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia