Grant, Jennifer’s team published research in Small in 14 | CAS: 56-05-3

Small published new progress about 56-05-3. 56-05-3 belongs to pyrimidines, auxiliary class Pyrimidine,Chloride,Amine,API, name is 2-Amino-4,6-dichloropyrimidine, and the molecular formula is C4H3Cl2N3, Product Details of C4H3Cl2N3.

Grant, Jennifer published the artcileAn Immobilized Enzyme Reactor for Spatiotemporal Control over Reaction Products, Product Details of C4H3Cl2N3, the publication is Small (2018), 14(31), n/a, database is CAplus and MEDLINE.

This paper describes a microfluidic chip wherein the position and order of two immobilized enzymes affects the type and quantity of reaction products in the flowing fluid. Assembly of the chip is based on a self-assembled monolayer presenting two orthogonal covalent capture ligands that immobilize their resp. fusion enzyme. A thiol-tagged substrate is flowed over a region presenting the first enzyme – which generates a product that is efficiently transferred to the second enzyme – and the second enzyme’s product binds to an adjacent thiol capture site on the chip. The amount of the three possible reaction products is quantified directly on the chip using self-assembled monolayers for matrix-assisted laser desorption/ionization mass spectrometry, revealing that the same microsystem can be spatiotemporally arranged to produce different products depending on the device design. This work allows for optimizing multistep biochem. transformations in favor of a desired product using a facile reaction and anal. format.

Small published new progress about 56-05-3. 56-05-3 belongs to pyrimidines, auxiliary class Pyrimidine,Chloride,Amine,API, name is 2-Amino-4,6-dichloropyrimidine, and the molecular formula is C4H3Cl2N3, Product Details of C4H3Cl2N3.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/Pyrimidine,
Pyrimidine – Wikipedia