Gronowitz, S.; Hoernfeldt, A. B.; Kristjansson, V.; Musil, T. published the artcile< On the synthesis of various thienyl- and selenienylpyrimidines>, Computed Properties of 3921-01-5, the main research area is halopyrimidine coupling thiopheneboronic acid; selenopheneboronic acid coupling halopyrimdine; pyrimidineboronic acid coupling bromothiophene; bromoselenophene coupling pyrimidineboronic acid; palladium coupling catalyst halopyrimidine; thienylpyrimidine; selenienylpyrimidine.
Various thienyl- and selenienylpyrimidines, including 5-substituted uracils, were prepared by the Pd(0)-catalyzed coupling between halopyrimidines I (R = H, Cl, Br, Me3CO, PhCH2O; R1 = Br, H) and thiopheneboronic acids and selenopheneboronic acids II [R2 = B(OH)2; X = S, Se, resp.]. 5-Bromouracil had to be protected as the tert-butoxy or benzyloxy derivative in order to achieve successful coupling. The compounds could also be obtained in a reversed manner, when pyrimidineboronic acids I [R = H, Me3CO; R1 = B(OH)2] were coupled with halothiophenes and haloselenophenes II (R2 = Br; X = S, Se).
Chemica Scripta published new progress about Coupling reaction. 3921-01-5 belongs to class pyrimidines, and the molecular formula is C4H2Br2N2, Computed Properties of 3921-01-5.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia