Guo, Chunfang published the artcileDirect C-H Difluoroalkylation of Heteroarenes with Difluoroalkyl Carboxylic Acids, Application In Synthesis of 42839-08-7, the main research area is difluoroalkylated heteroarene preparation; heteroarene difluoroalkyl carboxylic acid CH difluoroalkylation silver catalyst.
A new method for the difluoroalkylation of heteroaromatic compounds were developed by employing readily available difluoroalkyl carboxylic acids. This silver-catalyzed reaction proceeded under mild conditions and afforded a broad range of difluoroalkylated heteroarenes RCF2Ar [R = Me, Et, CH2CH2Ph; Ar = 4-CN-2-pyridyl, 4-PhO-2-pyridyl, 4-Me-2-quinolinyl, etc.] in moderate to good yields, including pyridines, pyrimidines, pyrazines, quinolines, quinoxalines as well as bioactive compounds
Asian Journal of Organic Chemistry published new progress about Fluoroalkanes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 42839-08-7 belongs to class pyrimidines, name is Ethyl pyrimidine-2-carboxylate, and the molecular formula is C7H8N2O2, Application In Synthesis of 42839-08-7.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia