Predicting mass loadings of sulfamonomethoxine, sulfamethoxazole, and lincomycin discharged into surface waters in Japanese river catchments was written by Hanamoto, Seiya;Yamamoto-Ikemoto, Ryoko;Tanaka, Hiroaki. And the article was included in Science of the Total Environment in 2021.Related Products of 1220-83-3 This article mentions the following:
Japanese strategies for the management of livestock waste suggest effluent discharge from livestock farms as major pathways of entry of veterinary antibiotics into surface waters. To aid control of their sources, we developed a model for predicting annual loads of antibiotics discharged into surface waters as effluent from livestock farms, sewage treatment plants, and households, using population, usage, excretion, removal, and fraction of livestock waste treated as wastewater. To verify the model, we monitored three antibiotics which are much used for livestock in Japan and are stable during river transport-i.e., sulfamonomethoxine (SMM), sulfamethoxazole (SMX), and lincomycin (LCM)-over one year in the Oyodo River, which has the most active swine farming area in Japan in its catchment. Concentrations and mass flows of SMM and SMX showed a sharp peak in winter, and those of LCM were also higher in winter than in summer in the river. Annual mass flows observed in the river and reported in three other Japanese rivers were within a range of 1/2 to 2 times the model estimates Effluent from swine farms contributed largely to mass flows of SMM and LCM in the rivers, while human wastewater from sewage treatment plants and households contributed partly to substantially to those of SMX. Estimated contributions of surface runoff from agricultural land to the annual mass flows in the rivers were < 1%, in agreement with the prediction made by limiting sources to effluent. Although other locations and antibiotics should be studied in the future, this first attempt at modeling the load of veterinary antibiotics discharged from livestock farms provides a new perspective on how to reduce movement of these compounds into surface waters in catchments where wastewater treatment is or could be used in managing livestock waste. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3Related Products of 1220-83-3).
4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3) belongs to pyrimidine derivatives. Pyrimidine also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. A Cu-catalyzed and 4-HO-TEMPO-mediated [3 + 3] annulation of commercially available amidines with saturated ketones enables an efficient and facile synthesis of structurally important pyrimidines via a cascade reaction of oxidative dehydrogenation/annulation/oxidative aromatization.Related Products of 1220-83-3
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia