Pyrimidine is a nitrogenous base similar to benzene (a six-membered ring) and includes cytosine, thymine, and uracil as bases used for DNA or RNA. 109-12-6, formula is C4H5N3, Name is Pyrimidin-2-amine. Pyrimidine also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. Related Products of 109-12-6.
Hazra, Ananta;Roy, Partha research published 《 A 4-methyl-2,6-diformylphenol based fluorescent chemosensor for Al3+》, the research content is summarized as follows. Authors report here synthesis, characterization, and Al3+ ion sensing properties of a 4-methyl-2,6-diformylphenol (DFP) based compound, 4-methyl-2,6-bis-(pyrimidin-2-ylimino)methylphenol (HMPM). It has been synthesized by condensation reaction between one eqv. of DFP and two eqv. of 2-aminopyrimidine in acetonitrile under mild conditions. Fluorescence intensity of HMPM increases by 12-fold in the presence of one eqv. of Al3+ in 10 mM HEPES buffer in water:DMSO (1:9, volume/volume) (pH 7.4). Other cations do not induce any appreciable increment in its fluorescence intensity. Its quantum yield and fluorescence life time enhance upon addition of Al3+. HMPM forms 1:1 complex with the cation. Detection limit has been determined as 1.27μM. Bare eye detection of Al3+ is possible with the help of HMPM. The probe has been used to detect Al3+ in ‘real sample’.
109-12-6, 2-Aminopyrimidine is a useful research compound. Its molecular formula is C4H5N3 and its molecular weight is 95.1 g/mol. The purity is usually 95%.
2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically., Related Products of 109-12-6
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia