Heterocyclic Communications | Cas: 18592-13-7 was involved in experiment

6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione (cas: 18592-13-7 Name: 6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione) was used in the synthesis of: 5-bromo-6-(chloromethyl)uracil, pteridine compounds, potential anticancer agents, substituted uracil pyridinium compounds, potential inhibitors of thymidine phosphorylase.

Name: 6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione《Synthesis of a novel fused tricyclic heterocycle, pyrimido[5,4-e][1,4]thiazepine, and its derivatives》 was published in 2013. The authors were Bazazan, Tahmineh;Bakavoli, Mehdi;Rahimizadeh, Mohammad;Eshghi, Hossein;Nikpour, Mohsen, and the article was included in《Heterocyclic Communications》. The author mentioned the following in the article:

Sequential treatment of 5-bromo-2,4-dichloro-6-(chloromethyl)pyrimidine with 2-aminothiophenol and secondary amines afforded a series of 2-[(5-bromo-2-chloro-6-aminopyrimidin-4-yl)methylthio]anilines. Reaction of the latter compounds with secondary amines in ethanol gave a family of new 5,11-dihydropyrimido[5,4-e][1,4]benzothiazepines I [R1 = N(Et)2, morpholinyl; R2 = pyrrolidinyl, piperidinyl, 1-methylpiperazinyl, etc.]. And 6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione (cas: 18592-13-7) was used in the research process.

6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione (cas: 18592-13-7 Name: 6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione) was used in the synthesis of: 5-bromo-6-(chloromethyl)uracil, pteridine compounds, potential anticancer agents, substituted uracil pyridinium compounds, potential inhibitors of thymidine phosphorylase.

Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia