Conformational analysis of 2′-fluoro-5-iodoarabinosyl-cytosine (FIAC) and 2′-fluoro-5-iodoribofuranosylcytosine (FIRC) was written by Hsu, Ling Yih; Liu, Kang Chien. And the article was included in Zhonghua Yaoxue Zazhi on December 31,1993.Application of 56632-83-8 The following contents are mentioned in the article:
Ribonucleoside I (R = H, R1 = F) is less active against HSV-1 and HSV-2 than arabinonucleoside I [R = F, R1 = H (II)]. The relationship between mol. conformation and antiviral activity of I is discussed. The rotational energy caused probably by the 2′-“”up””-fluoro substituent in the sugar moiety might lock II in an anti conformation, which might account for the potent antiviral activity. This study involved multiple reactions and reactants, such as 4-Amino-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (cas: 56632-83-8Application of 56632-83-8).
4-Amino-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (cas: 56632-83-8) belongs to pyrimidine derivatives. Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. A Cu-catalyzed and 4-HO-TEMPO-mediated [3 + 3] annulation of commercially available amidines with saturated ketones enables an efficient and facile synthesis of structurally important pyrimidines via a cascade reaction of oxidative dehydrogenation/annulation/oxidative aromatization.Application of 56632-83-8
56632-83-8;4-Amino-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one;The future of 56632-83-8;New trend of C9H12FN3O4;function of 56632-83-8