Hughes, David D. published the artcileOne or two-step Bohlmann-Rahtz heteroannulation of 6-aminouracil derivatives for the synthesis of pyrido[2,3-d]pyrimidines, Formula: C8H7N3O2, the main research area is aminouracil alkynone Bohlmann Rahtz heteroannulation; pyrido pyrimidine preparation.
The Michael addition-cyclodehydration of a 6-aminouracil and alkynone proceeds to give 5-deazapterin derivatives with total control of regiochem. This simple and facile cyclocondensation process is catalyzed by zinc(II) bromide or ytterbium(III) trifluoromethanesulfonate at 110°, providing the heteroannulated products in up to 94% yield.
Synlett published new progress about Bohlmann-Rahtz reaction. 36075-35-1 belongs to class pyrimidines, name is 7-Methylpyrido[2,3-d]pyrimidine-2,4-diol, and the molecular formula is C8H7N3O2, Formula: C8H7N3O2.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia