Synthesis of Pyrimidinyl Benzazolyl Urea Derivatives as Antimicrobial and Antioxidant Agents was written by Hussain Basha, N.;Narendra Babu, K.;Siva Shanker, P.;Dinneswara Reddy, G.;Padmaja, A.;Padmavathi, V.. And the article was included in Polycyclic Aromatic Compounds.Electric Literature of C16H13N3 This article mentions the following:
A library of pyrimidinyl benzazolyl urea derivatives were synthesized from pyrimidine-2-amine and Me benzazolylcarbamate in the presence of potassium tert-butoxide in DMF. The compounds with benzothiazolyl and benzimidazolyl moieties having chloro and nitro substituents on the aromatic ring exhibited prominent antibacterial activity against Bacillus subtilus. Nitro substituted pyrimidinyl benzothiazolyl urea and pyrimidinyl benzimidazolyl urea displayed prominent antifungal activity against Asperigellus niger. The compounds with benzoxazole moiety showed greater radical scavenging activity than those with benzothiazole and benzimidazole units. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8Electric Literature of C16H13N3).
4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. The pyrimidine derivatives can easily interact with enzymes, genetic materials, and bio components within the cell. We all know its importance to life – pyrimidine and purine bases are included in the structure of DNA and RNA.Electric Literature of C16H13N3
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia