In an article, author is Sweidan, Nuha, I, once mentioned the application of 3993-78-0, Name is 2-Amino-4-chloropyrimidine, molecular formula is C4H4ClN3, molecular weight is 129.55, MDL number is MFCD00038021, category is pyrimidines. Now introduce a scientific discovery about this category, Formula: C4H4ClN3.
Selective cyclization modes of methyl 3 ‘-heteroarylamino-2 ‘-(2,5-dichlorothiophene-3-carbonyl)acrylates. Synthesis of model (thienyl) pyrazolo- and triazolo[1,5-alpha]pyrimidines
Interaction of methyl 3-ethoxy-2-(2,5-dichloro-3-thenoyl)acrylate (I) with 3-aminopyrazole and 3- amino-1,2,4-triazole generated the respective pyrazolo [1,5-alpha]pyrimidine (4) and triazolo[1,5-alpha]pyrimidine (7). The formation of 4 entails selective and consecutive displacement of the 3-ethoxy and methoxy (ester) anions in I by 3-NH2 and 1-NH of 3-aminopyrazole. On the other hand, the formation of 7 implies selective displacement of 3-ethoxy in I by the ring-NH followed by cyclocondensation involving the keto group in I and 3-NH2 of aminotriazole. This latter selective displacement sequence is also followed by 3-amino-5-hydroxypyrazole in its reaction with I. The structures of the new compounds are supported by microanalytical and spectral data.
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Reference:
Pyrimidine | C4H4N2 – PubChem,
,Pyrimidine – Wikipedia