Introduction of a new synthetic route about 2,4,6-Triaminopyrimidine

Statistics shows that 1004-38-2 is playing an increasingly important role. we look forward to future research findings about 2,4,6-Triaminopyrimidine.

Synthetic Route of 1004-38-2, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.1004-38-2, name is 2,4,6-Triaminopyrimidine, molecular formula is C4H7N5, molecular weight is 125.13, as common compound, the synthetic route is as follows.

General procedure for thiocyanation of aminopyrimidine derivatives: Ammonium thiocyanate (3 mmol) and iodine (1.0 mmol) are added at room temperature to a stirred solution of the corresponding aminopyrimidine derivative (1.0 mmol) in methanol (10 mL). After completion of the reaction (TLC control), a sodium thiosulfate solution [20% (w/v)] is added to destroy the remaining iodine. The solid formed is filtered off, washed with water, and recrystallized from a methanol/water solution. For more details see Table 1 and Supplementary data.

Statistics shows that 1004-38-2 is playing an increasingly important role. we look forward to future research findings about 2,4,6-Triaminopyrimidine.

Reference:
Article; Rodriguez, Ricaurte; Camargo, Patricia; Sierra, Cesar A.; Soto, Carlos Y.; Cobo, Justo; Nogueras, Manuel; Tetrahedron Letters; vol. 52; 21; (2011); p. 2652 – 2654;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia