Introduction of a new synthetic route about 28485-17-8

The synthetic route of 28485-17-8 has been constantly updated, and we look forward to future research findings.

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 28485-17-8, name is 5-Carbethoxyuracil, the common compound, a new synthetic route is introduced below. SDS of cas: 28485-17-8

Method for svnthesising A. Id; B.2a A.1*d A.1d; Caesium carbonate (1.77 g, 5.43 mmol) is suspended in 10 mL DMSO, combined with carboxylic acid ester B.l-lc (1.00 g, 5.43 mmol) and stirred for 10 min at 200C. Then methyl iodide (0.338 muL, 5.43 mmol) is added and the mixture is stirred for 16 h at 200C. The crude product is purified by RP chromatography and carboxylic acid ester B.l-ld (HPLC-MS: tRet. = 0.64 min; MS(M+H)+ = 199; method FEC3) is obtained.

The synthetic route of 28485-17-8 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; ENGELHARDT, Harald; BOEHMELT, Guido; KOFINK, Christiane; KUHN, Daniel; McCONNELL, Darryl; STADTMUELLER, Heinz; WO2010/7114; (2010); A2;,
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