Adding a certain compound to certain chemical reactions, such as: 504-17-6, 4,6-Dihydroxy-2-mercaptopyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Computed Properties of C4H4N2O2S, blongs to pyrimidines compound. Computed Properties of C4H4N2O2S
General procedure: To a mixture of ethyl acetoacetate (1 mmol, 0.13 g) and hydrazine hydrate (1 mmol, 0.05 g) in magnetized water was added an aldehyde (1 mmol) and thiobarbituric acid (1mmol, 0.144 g). The reaction mixture was stirred at 50 C,and the reaction progress was monitored by TLC using chloroform as the eluent. After completion of the reaction, the precipitate formed was filtered and purified by recrystallization from ethanol to afford the desired product
At the same time, in my other blogs, there are other synthetic methods of this type of compound,504-17-6, 4,6-Dihydroxy-2-mercaptopyrimidine, and friends who are interested can also refer to it.
Reference:
Article; Bakherad, Mohammad; Doosti, Rahele; Keivanloo, Ali; Gholizadeh, Mostafa; Amin, Amir H.; Letters in Organic Chemistry; vol. 14; 7; (2017); p. 510 – 516;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia