Introduction of a new synthetic route about 61727-33-1

According to the analysis of related databases, 61727-33-1, the application of this compound in the production field has become more and more popular.

Related Products of 61727-33-1, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 61727-33-1, name is 5-Chloro-2-(methylthio)pyrimidine-4-carboxylic acid. This compound has unique chemical properties. The synthetic route is as follows.

(a) 5-Chloro-2-methylthio-4-pyrimidine carboxylic acid (30 g) was heated at 180-200 C. until all the solid had melted and the evolution of carbon dioxide had ceased (5 min). The residue was allowed to cool and then washed with several portions of chloroform. The chloroform washings were filtered to remove dark insoluble material and the filtrate was concentrated to give 5-chloro-2-methylthiopyrimidine as a pale brown crystalline solid (21 g, 89%), m.p. 55 C.

According to the analysis of related databases, 61727-33-1, the application of this compound in the production field has become more and more popular.

Reference:
Patent; ICI Australia Limited; US4248618; (1981); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia