Kinetics of the reaction of 2-thiouracil derivatives with chloroacetic acid amides was written by Jasinskas, L.;Urbonas, A.;Dienyte, J.. And the article was included in Lietuvos TSR Aukstuju Mokyklu Mokslo Darbai, Chemija ir Chemine Technologija in 1971.Application In Synthesis of 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one The following contents are mentioned in the article:
Rate constants and activation energies were determined for the reaction of 2-thiouracil anions (I; R = Me, NH2, CO2Bu; R1 = H, Me, Et) with ClCH2COR2 (R2 = NHPh, NEt2, morpholino, NHC6H4NO2-m). The reaction occurred by an SN2 mechanism. This study involved multiple reactions and reactants, such as 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3Application In Synthesis of 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one).
5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3) belongs to pyrimidine derivatives. Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. Pyrimidine derivatives have been used in a wide variety of pharmaceuticals including general anesthetics, anti-epilepsy medication, anti-malaria medication, drugs for treating high blood pressure, and HIV medication.Application In Synthesis of 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia