On September 1, 2017, Kang, Soyeong; Jang, Seok Hyeon; Lee, Juyeol; Kim, Dong-gil; Kim, Mijin; Jeong, Wook; Rhee, Young Ho published an article.Application of 4433-40-3 The title of the article was Pd-Catalyzed Regioselective Asymmetric Addition Reaction of Unprotected Pyrimidines to Alkoxyallene. And the article contained the following:
Catalytic asym. synthesis of N-heterocyclic glycosides free of protecting and directing groups is reported. The key reaction is highlighted by the atom-efficient and regioselective addition of unprotected pyrimidines to highly functionalized alkoxyallene. Numerous acyclic and cyclic N-heterocyclic glycosides are accessed with minimal formation of organic byproducts. The synthetic utility of the reaction is demonstrated by the first catalytic asym. synthesis of anticancer pharmaceutical (-)-Tegafur and stereoselective synthesis of an oxepane nucleoside derivative The experimental process involved the reaction of 5-(Hydroxymethyl)pyrimidine-2,4(1H,3H)-dione(cas: 4433-40-3).Application of 4433-40-3
The Article related to protecting group free heterocyclic glycoside enantioselective synthesis, regioselective addition unprotected pyrimidine alkoxyallene chiral catalysis, tegafur stereoselective synthesis oxepane nucleoside and other aspects.Application of 4433-40-3
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia