Treatment of genital herpes simplex virus infections in guinea pigs was written by Kern, Earl R.. And the article was included in UCLA Symposia on Molecular and Cellular Biology, New Series in 1984.Application of 69256-17-3 The following contents are mentioned in the article:
Intravaginal inoculation of guinea pigs with herpes simplex virus type 2 provides an excellent model for genital herpes in humans. The infection is characterized by local viral replication in the vaginal tract followed by the appearance of vesicular lesions on external genital skin. After recovery from the primary infection, spontaneous recurrent lesions appear on the external genitalia. Oral treatment with acyclovir [59277-89-3], 2′-deoxy-2′-fluoro-5-iodoarabinosylcytosin [69123-90-6], 2′-fluoro-5-iodoarabinosyluracil [69123-98-4], 2′-fluoro-5-methylarabinosyluracil [69256-17-3], 9-(1,3-dihydroxy-2′-propoxymethyl)guanine [82410-32-0], and i.m. treatment with recombinant human interferon-αA all reduced the severity of the primary infection. All compounds administered during recurrent disease also reduced the frequency of recurrent episodes, however, the frequency of recurrences returned to the level of controls when therapy was terminated. This study involved multiple reactions and reactants, such as 1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione (cas: 69256-17-3Application of 69256-17-3).
1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione (cas: 69256-17-3) belongs to pyrimidine derivatives. Pyrimidines are isomeric with two other forms of diazines: pyridazine, with the nitrogen atoms in the 1 and 2 positions; and pyrazine, with the nitrogen atoms in the 1 and 4 positions. Therapy for fungal infections is based mainly on four classes of antifungals: azoles, echinocandins, polyenes, and pyrimidine analogs.Application of 69256-17-3
69256-17-3;1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione;The future of 69256-17-3;New trend of C10H13FN2O5;function of 69256-17-3