Synthesis and properties of 2-(styrylthio)pyrimidin-6(1H)-ones was written by Kim, D. G.;Shmygarev, V. I.;Kharlampieva, E. P.;Vorob’ev, D. V.. And the article was included in Russian Journal of Organic Chemistry in 1997.Reference of 39083-15-3 The following contents are mentioned in the article:
Addition of 2-thioxo-1,2,3,4-tetrahydro-4-pyrimidinone derivatives (i.e. 2-thiouracil derivatives) to phenylacetylene in superbasic medium (DMSO-KOH) proceeds regio- and stereoselectively with formation of 2-(styrylthio)-6(1H)-pyrimidinone derivatives. Alkylation of these products with allyl bromide in alk. medium occurs at the N1 and oxygen atoms. 1-Allyl-2-(styrylthio)-6(1H)-pyrimidinone undergoes intramol. cyclization into oxazolo[3,2-c]pyrimidine system on treatment with iodine. This study involved multiple reactions and reactants, such as 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3Reference of 39083-15-3).
5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3) belongs to pyrimidine derivatives. Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. Drugs having the pyrimidine motif have manifested to exhibit gratifying biological activity like anticancer, antiviral, anti-inflammatory, antibacterial, and antihypertensive activities.Reference of 39083-15-3
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia