Kim, Juhyeon team published research in Molecules in 2017 | 2927-71-1

Formula: C4HCl2FN2, 2,4-Dichloro-5-fluoropyrimidine is a useful research compound. Its molecular formula is C4HCl2FN2 and its molecular weight is 166.97 g/mol. The purity is usually 95%.
2,4-Dichloro-5-fluoropyrimidine is an aromatic hydrocarbon that has been shown to inhibit the growth of mouse tumor cells in vitro. It also inhibits the production of amines by reacting with industrial chemicals and sodium carbonate. This compound has potent inhibitory activity against autoimmune diseases and cytotoxic potency on mcf-7 cells. Furthermore, 2,4-Dichloro-5-fluoropyrimidine has been shown to have a chlorinating effect on cancer cells., 2927-71-1.

The nomenclature of pyrimidines is straightforward. However, like other heterocyclics, tautomeric hydroxyl groups yield complications since they exist primarily in the cyclic amide form. 2927-71-1, formula is C4HCl2FN2, Name is 2,4-Dichloro-5-fluoropyrimidine. For example, 2-hydroxypyrimidine is more properly named 2-pyrimidone. A partial list of trivial names of various pyrimidines exists. Formula: C4HCl2FN2.

Kim, Juhyeon;Jo, Hanbyeol;Lee, Hyunseung;Choo, Hyunah;Kim, Hak Joong;Pae, Ae Nim;Cho, Yong Seo;Min, Sun-Joon research published 《 Identification of optically active pyrimidine derivatives as selective 5-HT2C modulators》, the research content is summarized as follows. A series of pyrimidine derivatives I [R = 2-F, 3-F, 4-F; R1 = H, Me; n = 0, 2] was synthesized and evaluated for their binding affinities toward 5-HT2C receptors. With regard to designed mols. I, the influence of size of alkyl ether and the absolute configuration of a stereogenic center on the 5-HT2C binding affinity and selectivity was studied. The most promising diastereomeric mixtures I [R = 3-F, 4-F; R1 = Me; n = 0] were selected in the initial radioligand binding assay and they were further synthesized as optically active forms starting from optically active alcs. RC6H4CH2CH(Me)OH [stereo – R or S] by enzymic kinetic resolution Pyrimidine analog I [R = 4-F, R1 = Me, n = 0, stereo – (R,R)] displayed an excellent 5-HT2C binding affinity with good selectivity values against a broad range of other 5-HT receptor subtypes.

Formula: C4HCl2FN2, 2,4-Dichloro-5-fluoropyrimidine is a useful research compound. Its molecular formula is C4HCl2FN2 and its molecular weight is 166.97 g/mol. The purity is usually 95%.
2,4-Dichloro-5-fluoropyrimidine is an aromatic hydrocarbon that has been shown to inhibit the growth of mouse tumor cells in vitro. It also inhibits the production of amines by reacting with industrial chemicals and sodium carbonate. This compound has potent inhibitory activity against autoimmune diseases and cytotoxic potency on mcf-7 cells. Furthermore, 2,4-Dichloro-5-fluoropyrimidine has been shown to have a chlorinating effect on cancer cells., 2927-71-1.

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia