The nomenclature of pyrimidines is straightforward. However, like other heterocyclics, tautomeric hydroxyl groups yield complications since they exist primarily in the cyclic amide form. 4595-59-9, formula is C4H3BrN2, Name is 5-Bromopyrimidine. For example, 2-hydroxypyrimidine is more properly named 2-pyrimidone. A partial list of trivial names of various pyrimidines exists. Safety of 5-Bromopyrimidine.
Klikar, Milan;Georgiou, Dimitris;Polyzos, Ioannis;Fakis, Mihalis;Ruzickova, Zdenka;Pytela, Oldrich;Bures, Filip research published 《 Triphenylamine-based fluorophores bearing peripheral diazine regioisomers. Synthesis, characterization, photophysics and two-photon absorption》, the research content is summarized as follows. Six tripodal push-pull fluorophores with D-(π-A3) arrangement were designed and synthesized. The structure of these fluorophores consists of a central electron-donating triphenylamine core and peripheral electron-withdrawing diazine units (pyridazine, pyrimidine, and pyrazine moieties), which are linked by an ethynylene π-spacer. The preparation of the fluorophores involves 3-fold Sonogashira cross-coupling reaction starting from the key tris(4-ethynylphenyl)amine intermediate. The structure and spatial arrangement of 2 fluorophores were completely confirmed by x-ray anal. Thermal and electrochem. behavior of prepared fluorophores were studied by DSC and cyclic voltammetry. Their linear optical properties were examined by UV-visible absorption, steady-state and time resolved fluorescent spectroscopy while 2 PA anal. was used for a study of the nonlinear optical response. Exptl. data were supported by DFT calculations Based on the exptl. as well as theor. data, structure-property relations were thoroughly revealed.
4595-59-9, 5-Bromopyrimidine is a reactive intermediate that is used in the synthesis of 4-methoxyphenylboronic acid. 5-Bromopyrimidine has been shown to be nucleophilic, reacting with β-amino acids under basic conditions to form the corresponding 2-bromo amide. It also undergoes cross-coupling reactions with halides and can be used as a building block for other organic compounds. 5-Bromopyrimidine has optical properties that are characteristic of aromatic molecules, including strong absorption bands in the ultraviolet region and visible light region.
5-Bromopyrimidine undergoes direct metallation with lithuium diisopropylamide to yield 4-lithio-5-bromopyrimidine., Safety of 5-Bromopyrimidine
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia