So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Foley, G. E.; McCarthy, R. E.; Binns, V. M.; Snell, E. E.; Guirard, B. M.; Kidder, G. W.; Dewey, V. C.; Thayer, P. S. researched the compound: 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride( cas:148-51-6 ).Recommanded Product: 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride.They published the article 《Comparative study of the use of microörganisms in the screening of potential antitumor agents》 about this compound( cas:148-51-6 ) in Annals of the New York Academy of Sciences. Keywords: CYTOTOXIC DRUGS; MICROORGANISMS. We’ll tell you more about this compound (cas:148-51-6).
Collaborative studies were organized to include 16 microbial systems, with bacteria, fungi, and protozoa as the assay microörganisms. A series of 200 compounds were studied. It appears that 95% of the compounds adjudged to be tumor-active in animal assays can be detected by virtue of their inhibitory effects on microörganisms, with as few as 4 selected bioassay systems. 34 references
After consulting a lot of data, we found that this compound(148-51-6)Recommanded Product: 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia