《Synthesis of Indolizines via Reaction of 2-Substituted Azaarenes with Enals by an Amine-NHC Relay Catalysis》 was written by Li, Hongxian; Li, Xiangmin; Yu, Yang; Li, Jianjun; Liu, Yuan; Li, Hao; Wang, Wei. Recommanded Product: 63155-11-3 And the article was included in Organic Letters on April 21 ,2017. The article conveys some information:
A metal-free catalytic strategy for the facile synthesis of biol. relevant mol. architectures indolizines and imidazopyridines was developed. The process is promoted by amine and N-heterocyclic carbene (NHC) relay catalysis via Michael addition-[3 + 2] fusion of simple azaarenes and α,β-unsaturated aldehydes. The preparative power is demonstrated in the synthesis of anxiolytic drug saripidem via two simple 1-pot operations with overall 45% yield. The experimental process involved the reaction of Ethyl 2-(pyrimidin-2-yl)acetate(cas: 63155-11-3Recommanded Product: 63155-11-3)
Ethyl 2-(pyrimidin-2-yl)acetate(cas: 63155-11-3) is a member of pyrimidine. Pyrimidine derivatives are an important class of N-heterocycles. They are well-known for their wide spectrum of promising biological activities such as antitumors, bactericidals, and fungicidal.Recommanded Product: 63155-11-3
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia