Li, Jiang et al. published their research in Chemosphere in 2021 | CAS: 1220-83-3

4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3) belongs to pyrimidine derivatives. Pyrimidines are isomeric with two other forms of diazines: pyridazine, with the nitrogen atoms in the 1 and 2 positions; and pyrazine, with the nitrogen atoms in the 1 and 4 positions. As nucleotides in DNA and RNA, pyrimidine nucleotide derivatives have a wide range of biological applications. For example, pyrimidine derivatives are useful in DNA repair studies involving cancer and epigenetics.Application In Synthesis of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide

Photocatalytic degradation of sulfamonomethoxine by mesoporous phosphorus-doped titania under simulated solar light irradiation was written by Li, Jiang;Su, Qi;Yuan, Huayu;Zhang, Lin;Hou, Li’an;Wang, Yuehu;Liu, Baojun;Wang, Bing;Li, Yancheng. And the article was included in Chemosphere in 2021.Application In Synthesis of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide This article mentions the following:

Photocatalytic degradation of sulfamonomethoxine (SMM) by mesoporous phosphorus-doped TiO2 (P-TiO2) was studied under simulated solar light irradiation The morphol. structure and chem. composition of P-TiO2 were analyzed by XRD, SEM, HRTEM, BET, XPS and FTIR. Using the central composite design (CCD) of response surface methodol. (RSM), the degradation of SMM was investigated with a range of antibiotic concentrations (4-8 mg L-1), catalyst dosages (400-900 mg L-1), P doping amounts (5-15 wt%) and irradiation time (90-150 min). The Ti-O-P bond formed during the calcination of TiO2, thereby generating plate-like P-TiO2, where P was uniformly distributed. Phosphorus doping can stabilize anatase TiO2, which has a larger sp. surface area and a lower average particle and pore size than bare TiO2. The result obtained from the RSM model showed a significant correlation between the predicted values and the exptl. results of SMM degradation (P < 0.05). Under the optimal exptl. conditions (antibiotic concentration = 6 mg/L, catalyst dosage = 800 mg/L, P doping = 5 wt% and irradiation time = 90 min), the degradation rate of SMM was 99.51%, and the TOC was 50%. Toxicity showed a considerable reduction towards Vibrio-qinghaiensis sp.-Q67 after SMM photocatalytic degradation Through free radical capture experiments, LC-MS detection and DFT calculations, the possible photocatalytic degradation mechanism of SMM using P-TiO2 as the catalyst was revealed. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3Application In Synthesis of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide).

4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3) belongs to pyrimidine derivatives. Pyrimidines are isomeric with two other forms of diazines: pyridazine, with the nitrogen atoms in the 1 and 2 positions; and pyrazine, with the nitrogen atoms in the 1 and 4 positions. As nucleotides in DNA and RNA, pyrimidine nucleotide derivatives have a wide range of biological applications. For example, pyrimidine derivatives are useful in DNA repair studies involving cancer and epigenetics.Application In Synthesis of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia