Lin, J. C. et al. published their research in International Congress Series in 1985 | CAS: 69256-17-3

1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione (cas: 69256-17-3) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.SDS of cas: 69256-17-3

Effects of nucleoside analogs in inhibition of Epstein-Barr virus was written by Lin, J. C.; Nelson, D. J.; Lambe, C. U.; Choi, E. I.; Pagano, J. S.. And the article was included in International Congress Series in 1985.SDS of cas: 69256-17-3 The following contents are mentioned in the article:

The relative antiviral potency of several nucleoside analogs against Epstein-Barr virus infection in P3HR-1 cells was 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodocytosine (I) [69123-90-6] = 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil (II) [69123-98-4] > 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-thymine (III) [69256-17-3] > BW B759U (IV) [82410-32-0] > E-5-(2-bromovinyl)-2′-deoxyuridine (V) [69304-47-8] > acyclovir (VI); the relative therapeutic efficacy (ratio of cytotoxicity to antiviral potency) was V > IV > I > VI > II > III. IV was rapidly and markedly phosphorylated by virus-infected Raji cells; this effect was 100-fold greater than for VI. The results are discussed with respect to the prolonged inhibitory action of the nucleoside analogs against Epstein-Barr virus replication. This study involved multiple reactions and reactants, such as 1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione (cas: 69256-17-3SDS of cas: 69256-17-3).

1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione (cas: 69256-17-3) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.SDS of cas: 69256-17-3

69256-17-3;1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione;The future of 69256-17-3;New trend of C10H13FN2O5;function of 69256-17-3