Little discovery in the laboratory: a new route for 65090-78-0

There is still a lot of research devoted to this compound(SMILES:O=C(O)C(Br)COC)Recommanded Product: 65090-78-0, and with the development of science, more effects of this compound(65090-78-0) can be discovered.

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 2-Bromo-3-methoxypropanoic acid, is researched, Molecular C4H7BrO3, CAS is 65090-78-0, about New and alternate synthesis of lacosamide with chemoenzymatic method, the main research direction is enzymic resolution racemic lacosamide; lacosamide enantiopure preparation.Recommanded Product: 65090-78-0.

Lacosamide [(R)-2-acetamido-N-benzyl-3-methoxy propionamide] 5 is a novel antiepileptic drug. Lacosamide was prepared by a chem. method with enzymic resolution of racemic lacosamide. Herein is reported an expedient four-steps enantioselective synthesis of lacosamide 5 beginning with Me 2,3-dibromo propionate 1. A new resolution process catalyzed by Novozyme 435. The products were obtained in very good yields and in a state of high purity. All the newly synthesized compounds (2-5) were characterized by their spectral (IR, 1H NMR, C13 NMR and MS) data.

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Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia