On July 21, 2017, Liu, Shuangwei published a patent.Quality Control of 2-Methyl-7H-pyrrolo[2,3-d]pyrimidine The title of the patent was Process for preparation of pyrrolo[2,3-d]pyrimidine derivative for treating rheumatoid arthritis. And the patent contained the following:
The invention relates to preparation of pyrrolo[2,3-d]pyrimidine derivative of formula I, wherein R is Me, CF3, F, Ph for treating rheumatoid arthritis. Compound I was prepared via bromination of 2-Me-7-H-pyrrolo[2,3-d]pyrimidine followed by carboxylation, acylation, condensation and reaction with morpholine. The medicine has obvious therapeutic action to RA, and can be used for treating rheumatoid arthritis. The experimental process involved the reaction of 2-Methyl-7H-pyrrolo[2,3-d]pyrimidine(cas: 89792-07-4).Quality Control of 2-Methyl-7H-pyrrolo[2,3-d]pyrimidine
The Article related to pyrrolopyrimidine derivative preparation rheumatoid arthritis, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Quality Control of 2-Methyl-7H-pyrrolo[2,3-d]pyrimidine
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia