Susceptibility of several strains of varicella-zoster virus to 5-substituted derivatives of 2′-deoxyuridine and 1-β-D-arabinofuranosyluracil was written by Machida, Haruhiko; Kuninaka, Akira; Yoshino, Hiroshi. And the article was included in International Congress Series in 1982.Product Details of 69256-17-3 The following contents are mentioned in the article:
In confluent monolayers of human embryonic lung fibroblast cells infected with varicella-zoster virus, 5-bromovinylarabinosyluracil (I) [77181-69-2] and 5-chlorovinylarabinosyluracil [77181-70-5] were the most potent of the 9 thymidine analogs in inhibiting plaque formation. There was some variability in the susceptibility of different strains of varicella-zoster virus to the thymidine analogs. The susceptibility of varicella-zoster virus to these compounds was different than that of herpes simplex virus type 1 and type 2. This study involved multiple reactions and reactants, such as 1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione (cas: 69256-17-3Product Details of 69256-17-3).
1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione (cas: 69256-17-3) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. Drugs having the pyrimidine motif have manifested to exhibit gratifying biological activity like anticancer, antiviral, anti-inflammatory, antibacterial, and antihypertensive activities.Product Details of 69256-17-3
69256-17-3;1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione;The future of 69256-17-3;New trend of C10H13FN2O5;function of 69256-17-3