Manzoor, Saira published the artcileTetrazole and Azido Derivatives of Pyrimidine: Synthesis, Mechanism, Thermal Behaviour & Steering of Azido-Tetrazole Equilibrium, Product Details of C4H3Cl2N3, the publication is ChemistrySelect (2020), 5(18), 5414-5421, database is CAplus.
A new family of pyrimidine modified tetrazole & azido derivatives I (R = pyrimidin-2-yl, 2,6-dimethoxypyrimidin-4-yl, 6-azidopyrimidin-4-yl, etc.), II, III, IV and tetrazolo[1,5-c]pyrimidin-5-amine was developed using the conventional and nucleophilic substitution methods. The 1H-(tetrazol-1-yl)pyrimidine I compounds were prepared via traditional cycloaddition and condensation method. The compounds tetrazolo[1,5-a]pyrimidine (II, III and IV), azido-(1H-tetrazol-1-yl)pyrimidine I (R = 6-azidopyrimidin-4-yl and 4-azido-6-chloropyrimidin-2-yl) and tetrazolo[1,5-c]pyrimidin-5-amine were synthesized by simultaneously introducing conventional and nucleophilic substitution approaches. The latter technique was easy to process and reduce the synthesis time. The factors (solvent, temperature, steric effect, electron-donating groups, and electron-withdrawing groups) were found responsible for steering the azido-tetrazole equilibrium in the compounds II, III, IV and tetrazolo[1,5-c]pyrimidin-5-amine. All the prepared compounds were well characterized including single-crystal X-ray diffraction structures of some compounds Thermal behavior was investigated by differential scanning calorimetry (DSC) and thermal gravimetric anal. (TGA). The current work is significant to the development of a new class of pyrimidine modified tetrazole and azido derivatives in sense of easy reaction approach, good to excellent yields, safe process, and simple work-ups.
ChemistrySelect published new progress about 56-05-3. 56-05-3 belongs to pyrimidines, auxiliary class Pyrimidine,Chloride,Amine,API, name is 2-Amino-4,6-dichloropyrimidine, and the molecular formula is C4H3Cl2N3, Product Details of C4H3Cl2N3.
Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/Pyrimidine,
Pyrimidine – Wikipedia