McGee, Danny P. C.; Martin, John C.; Verheyden, Julien P. H. published the artcile< Synthesis of the 7-deaza and 5-aza-7-deaza purine analogs of the antiherpes agent 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine (DHPG)>, Recommanded Product: 4-Methoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amine, the main research area is pyrrolopyrimidinone acyclic nucleoside analog; imidazotriazinone acyclic nucleoside analog; acyclic nucleoside pyrrolopyrimidinone imidazotriazinone; virucide acyclic nucleoside; DHPG analog; hydroxypyropoxymethylpyrrolopyrimidinone amino; hydroxypropoxymethylimidazotriazinone amino.
DHPG analogs I and II were prepared Reaction of 2-amino-4-methoxypyrrolo[2,3-d]pyrimidine with 1,3-dibenzyloxy-2-(chloromethyl)glycerol under phase-transfer conditions gave a product which on sequential treatment with p-MeC6H4SK (to cleave the Me ether) and BBr3 (for debenzylation) gave I. Reaction of 2-acetamidoimidazo[1,2-a]-s-triazin-4-one with 1,3-dibenzyloxy-2-(acetoxymetyl)glycerol gave a product, which on debenzylation (by catalytic transfer hydrogenation) and then deacetylation gave II. I and II were inactive against herpes simplex virus types I and II in cell culture.
Journal of Heterocyclic Chemistry published new progress about Antiviral agents. 84955-32-8 belongs to class pyrimidines, and the molecular formula is C7H8N4O, Recommanded Product: 4-Methoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amine.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia