On March 31, 1986, Mikhaleva, M. A.; Kolesnichenko, G. A.; Rubina, K. I.; Gol’dberg, Yu. Sh.; Savel’ev, V. A.; Leitis, L. Ya.; Shimanskaya, M. V.; Mamaev, V. P. published an article.Quality Control of 5-Phenylpyrimidine-2-carboxylic acid The title of the article was Synthesis of 5-arylpyrimidine-2-carboxylic acids and liquid crystalline properties of their aryl esters. And the article contained the following:
5-Arylpyrimidine-2-carboxylic acids I (R = H, MeO, BuO, R1 = H) were prepared by hydrolysis of 5-aryl-2-cyanopyrimidines and by phase-transfer catalyzed oxidation of 5-aryl-2-styrylpyrimidines. Aryl esters of these acids I (R1 = Ph, substituted Ph) were obtained and their liquid crystalline properties were studied. p-Substituted 5-phenyl-2-pyrimidinecarboxylates do not exhibit mesomorphism, but introduction of a butoxy group in the para position of the pyrimidine attached Ph ring leads to the appearance of nematic properties. In addition, aryl 5-phenylpyrimidincarbonyloxybenzoates are nematic liquid crystals with a thermally stable mesophase at 50-80° during their lifetimes. The experimental process involved the reaction of 5-Phenylpyrimidine-2-carboxylic acid(cas: 85386-20-5).Quality Control of 5-Phenylpyrimidine-2-carboxylic acid
The Article related to aryl arylpyrimidinecarboxylate liquid crystal, pyrimidinecarboxylic acid liquid crystal, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Quality Control of 5-Phenylpyrimidine-2-carboxylic acid
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia