Microwave promoted efficient synthesis of substituted uracils and thiouracils under solvent-free conditions was written by Mojtahedi, Mohammad M.;Saidi, Mohammad R.;Shirzi, Jafar S.;Bolourtchian, Mohammad. And the article was included in Synthetic Communications in 2002.Related Products of 39083-15-3 The following contents are mentioned in the article:
Several substituted uracils and thiouracils were synthesized in good yields by one-pot condensation reaction of Me or Et β-ketoesters and urea (or thiourea) in solvent-free conditions under microwave irradiation and in short time. This study involved multiple reactions and reactants, such as 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3Related Products of 39083-15-3).
5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3) belongs to pyrimidine derivatives. The pyrimidine nitrogenous bases are derived from the organic compound pyrimidine through the addition of various functional groups. Drugs having the pyrimidine motif have manifested to exhibit gratifying biological activity like anticancer, antiviral, anti-inflammatory, antibacterial, and antihypertensive activities.Related Products of 39083-15-3
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia