Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 139756-21-1, Name is 5-(2-Ethoxyphenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one, SMILES is O=C1C(N(C)N=C2CCC)=C2N=C(C3=CC=CC=C3OCC)N1, belongs to pyrimidines compound. In a document, author is Debnath, Pradip, introduce the new discover, Formula: C17H20N4O2.
Synthesis of functionalized pyrimidouracils by ruthenium-catalyzed oxidative insertion of (hetero)aryl methanols into N-uracil amidines
A dehydrogenative coupling of N-uracil amidines with (hetero)aryl methanols has been developed, allowing for the facile synthesis of a broad range of structurally diverse pyrimidouracils. By applying [RuCl2(p-cymene)](2)/Cs2CO3 as an efficient catalytic system, the easily available, cheap (hetero)aryl methanols were firstly employed for oxidative insertion/C-H amination into the N-uracil amidines, providing highly functionalized pyrimido[4,5-d]pyrimidine-2,4-diones. Due to the better stability of alcohols than aldehydes, this synthetic protocol is applicable to a broad range of alcoholic substrates and does not required any protection during the whole preparation process. The presented protocol has the potential to prepare valuable products which cannot be accessed presently or extremely arduous to procure by following regular procedure. Hence, this is a remarkably improved protocol compared with the existing methodologies. The overall reaction sequence is an effective oxidation-imination-cyclization tandem process catalyzed by ruthenium catalyst.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 139756-21-1 is helpful to your research. Formula: C17H20N4O2.
Reference:
Pyrimidine | C4H4N2 – PubChem,
,Pyrimidine – Wikipedia