Mosti, Luisa’s team published research in Journal of Heterocyclic Chemistry in 1983-06-30 | CAS: 66373-25-9

Journal of Heterocyclic Chemistry published new progress about Cyclocondensation reaction. 66373-25-9 belongs to class pyrimidines, name is 1-(2-Amino-4-methylpyrimidin-5-yl)ethanone, and the molecular formula is C7H9N3O, Synthetic Route of 66373-25-9.

Mosti, Luisa published the artcileReaction of 2-dimethylaminomethylene-1,3-diones with dinucleophiles. III. Synthesis of 5-acylpyrimidines and 7,8-dihydroquinazolin-5(6H)-ones, Synthetic Route of 66373-25-9, the main research area is methylaminomethylene dione cyclocondensation dinucleophile; pyridine acyl; quinazolinone dihydro.

The reaction of open-chain and cyclohexane sym-2-dimethylaminomethylene-1,3-diones with amidines and guanidine in refluxing ethanol gave, generally in good yields, acylpyrimidines I (R = Me, Me2CH, Me3C, Ph; R1 = H, Me, Ph, NH2) and dihydroquinazolinones II (X = CH2, CMe2, CHPh) resp. With formamidine (and in part acetamidine), 2-formylimino-1,3-diones, e.g., III, were formed as sole products or mixtures with pyrimidines or dihydroquinazolinones.

Journal of Heterocyclic Chemistry published new progress about Cyclocondensation reaction. 66373-25-9 belongs to class pyrimidines, name is 1-(2-Amino-4-methylpyrimidin-5-yl)ethanone, and the molecular formula is C7H9N3O, Synthetic Route of 66373-25-9.

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia