Mustafin, A. G.; Suyundukova, M. V.; Gataullin, R. R.; Spirikhin, L. V.; Abdrakhmanov, I. B.; Tolstikov, G. A. published an article in Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). The title of the article was 《Transformations of β-D-xylofuranosyl nucleosides. The effective synthesis of 2′,3′-dideoxy-2′,3′-didehydrothymidine》.SDS of cas: 122567-97-9 The author mentioned the following in the article:
We have shown earlier that heating 1-(2′-O-tosyl-3′,5′-di-O-benzoyl-β-D-xylofuranosyl)thymine with NaI leads to a mixture of 2,2′-anhydronucleoside and 5′-O-benzoyl-2′,3′-dideoxy-2′,3′-didehydrothymidine. We now continue our search for efficient methods of introducing a double bond at position 2′,3′ of the sugar moiety and found that the reaction of a 2,2′-anhydro compound with HI in anhydrous 1,2-dimethoxyethane leads to a 2′,3′-didehydronucleoside. The experimental part of the paper was very detailed, including the reaction process of ((2S,5R)-5-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dihydrofuran-2-yl)methyl benzoate(cas: 122567-97-9SDS of cas: 122567-97-9)
((2S,5R)-5-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dihydrofuran-2-yl)methyl benzoate(cas: 122567-97-9) belongs to pyrimidine. Pyrimidine nucleotide derivatives have a wide range of biological applications. For example, pyrimidine derivatives are useful in DNA repair studies involving cancer and epigenetics.SDS of cas: 122567-97-9
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia